Unethical: Why Bristol University SMILE trial should not have been conducted with chronically ill children
If it should have been conducted at all, the first clinical trial of Lightning Process should not have been conducted with chronically ill children. Safety and efficacy had neither been established with adults, nor healthy children.
What should be done about the MEGA (ME/CFS Epidemiology and Genetics Alliance) project? Concerns and response
The MEGA (ME/CFS Epidemiology and Genetics Alliance) promises to be an extremely important scientific project, but important issues remain before patients can comfortably participate.
Stakeholders from around the world are responding to UK Tribunal ordering sharing with public of data from the PACE chronic fatigue syndrome trial data.
Why patients should not enroll in a clinical trial of video gaming treatment for chronic fatigue syndrome
Patients have right to decline to participate in a clinical trial that is scientifically unsound, likely to contribute misinformation to the existing scientific literature, and that has unresolved safety concerns.
Updated May 22, 2016. I have added an opening summary, as well as a few links for readers who may want to learn more about IBS as a physical health problem about which we are learning a lot, not a mental health issue. Irritable bowel syndrome (IBS) has symptoms in common with other physical conditions. […]
Ellen Langer: genius or quack –or master self-marketer? Another lesson we need to be wary of trustworthiness and authority established by awards or celebrity status. We need to be skeptical of the publicity machines that confer celebrity status on “scientists.’ We need to be skeptical about scientists who gather such recognition. It could be just […]
A prominent notice has appeared on the PLOS One article McCrone P, Sharpe M, Chalder T, Knapp M, Johnson AL, et al. (2012) Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis. PLOS ONE 7(8): e40808. doi: 10.1371/journal.pone.0040808 PLOS ONE notice: Update on follow up Posted […]
PLOS One allows authors of experimercial undeclared conflicts of interest, restrictions on access to data
While checking what PLOS One had done to address my complaints about authors’ repeated undeclared conflicts of interest, I made some troubling discoveries. The PLOS One Academic Editor for one of the papers was from Harvard Medical School, the same as the offending authors. PLOS One had agreed to absurd restrictions on the availability of […]
Repeated signals that The BMJ is moving forward while editors of other key medical journals try to undermine data sharing. Institutions are stiffening their resistance to release of the promised PACE trial data from the PLOS One article. This threatens to splinter the movement for routine data sharing. But The BMJ continues to support for […]
In bringing up “protecting patient privacy” in refusing to release the PACE trial data published in PLOS One, King’s College, London is doing the Shuck ‘N’ Jive. As covered in a recent blog post, King’s College London issued a press release reiterating their refusal to release the PACE PLOS One data. A close read of […]