Mind the Brain

Is Donald Trump suffering from Pick’s Disease (frontotemporal dementia)?

Changing the conversation about Donald Trump’s fitness for office from whether he has a personality disorder to whether he has an organic brain disorder.

Using F1000 “peer review” to promote politics over evidence about delivering psychosocial care to cancer patients

The F 1000 platform allowed authors and the reviewers whom they nominated to collaborate in crafting more of their special interest advocacy that they have widely disseminated elsewhere. Nothing original in this article and certainly not best evidence!

In a classic study of early childhood abuse and neglect, effects on later mental health nearly disappeared when….

Controls were introduced for life events that occurred between the childhood abuse and neglect and assessment of mental health outcomes in adulthood. Adults who had objective reports of abuse and neglect in their childhood were matched with adults who were from similar backgrounds, but without such abuse and neglect.

Stop using the Adverse Childhood Experiences Checklist to make claims about trauma causing physical and mental health problems

Scores on the adverse childhood experiences (ACE) checklist (or ACC) are widely used in making claims about the causal influence of childhood trauma on mental and physical health problems. Does anyone making these claims bother to look at how the checklist is put together and consider what a summary score might mean?

School-Based Mindfulness Based Stress-Reduction Program (MBSR) fails to deliver positive results

No positive effects found for Jon Kabat-Zinn’s Mindfulness Based Stress-Reduction Program with middle and high school students. Evidence of deterioration was found in some subgroup analyses.

Did a placebo affect allergic reactions to a pin prick or only in the authors’ minds?

Can placebo effects be harnessed to improve treatment outcomes? Stories of a placebo changing bodily function are important in promoting mind-body medicine, but mostly turn out to be false positives. Was this one an exception?

“It’s certainly not bareknuckle:” Comments to a journalist about a critique of mindfulness research

We can't assume authors of mindfulness studies are striving to do the best possible science, including being prepared for the possibility of being proven incorrect by their results.

Reflections on my tour of the Soteria Project at St Hedwig Hospital, Berlin

A fabulous, enlightened experiment in Berlin with humane treatment of patients suffering severe mental disorder that we cannot reproduce in the United States.

Power pose: II. Could early career investigators participating in replication initiatives hurt their advancement?

Participation in attempts to replicate seriously flawed studies might be seen as bad judgment, when there many more opportunities to demonstrate independent, critical thinking.